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Other researchers have also confirmed the relevant role of CYP4F2 V433M polymorphism in the pharmacogenetics of coumarin anticoagulants (55,56)

Procyanidins from hawthorn ( Crataegus pinnatifida ) alleviate lipid metabolism disorder via inhibiting insulin resistance and oxidative stress, normalizing the gut microbiota structure and intestinal barrier, and further suppressing hepatic inflammation and lipid accumulation

Iron is also found in the brain, providing conditions conductive to ferroptosis in Wilson disease

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