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Then, in 2015, Lee and colleagues identified a previously overlooked open reading frame within the 12S ribosomal RNA gene of mtDNA and found that it encodes a functional peptide, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) [1]

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Hassan MH, et al

10.46497/ArchRheumatol.2020.7633 [DOI] [PMC free article] [PubMed] [Google Scholar] 73.Peng YF, Wang JL, Pan GG

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International Studies: Glutathione system enhancement for cardiac protection (Nature Cell Death & Disease, 2023) Overview of the role of the glutathione system in protecting the cardiovascular system from oxidative stress and ferroptosis