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(Biochem Pharmacol 2018) documented a reduction of -35% in white adipose tissue, -40% in adipocyte volume, -5.1% in body weight and -30% in plasma cholesterol in just 11 days in obese mice (DIO), without any change in food intake

Although it was first identified in gastric juice , today it is synthesized in laboratories for research purposes

NNMT becomes a metabolic problem when it is overexpressed which is precisely what happens in obesity