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Front Physiol 12:724506

As a corollary, chronic inflammation and age increase differentially methylated DNA and subsequent cancer risk, especially breast and colorectal cancers (Benelli et al., 2021)

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3 Pathophysiology of depression 3.1 Monoaminergic dysfunction Monoaminergic disruptions especially those related to serotonin (5-HT), norepinephrine (NE), and dopamine (DA), constitute a fundamental and classical mechanism in the pathophysiological framework of depression

This difference has practical implications for dosing