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84,85 In a crossover study of healthy dogs taking the steroid prednisolone, SAMe supplementation at 10 mg/kg body weight twice daily for 42 days was found to reduce blood markers of liver oxidative damage, although the dogs still developed signs of steroid-induced liver disease

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It helps protect and heal the gut lining, muscles, tendons, and nerves

45 Because this study had no control group it is impossible to establish whether the observed benefits were due to a placebo effect

El KPV ampla el rango hacia modelos de inflamacin intestinal, donde su accin sobre el eje melanocortina y la va NF-B resulta de inters