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Nicotine and its metabolic products affect the renal vessels and can indirectly change some parameters

That answers how nicotine pouches work in simple terms: oral absorption rather than inhalation

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The nicotine in vape products causes significant damage to the entire cardiovascular system, particularly in the heart

Following the ruling, all tobacco packaging in the UK must be olive green and picture health warnings must cover 65% of the front and back of every packet of cigarettes, with additional warnings on the top

I countered that those differences are likely explained by other factors, including Americas more comprehensive reporting, higher chronic-disease rates, older population, and colder climate