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Jafari-Nozad AM, Jafari A, Yousefi S, Bakhshi H, Farkhondeh T, Samarghandian S

In REDEFINE 1, adverse events were mainly gastrointestinal (79.6% in the CagriSema group vs 39.9% with placebo) including nausea (55% vs 12.6%), constipation (30.7% vs 11.6%), and vomiting (26.1% vs 4.1%)

[9] Transient itching or rash has been noted in some cases, possibly indicating a mild sensitivity reaction

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CXCR4-modified CAR-T cells suppresses MDSCs recruitment via STAT3/NF-B/SDF-1 axis to enhance efficacy against pancreatic cancer