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Likewise, endothelial cells are regulating mucosal immune homeostasis, acting as "gatekeepers", controlling leukocyte accumulation in the interstitial compartment

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IM injections : SC administration offers slightly better bioavailability (75%) compared to IM (63%), though IM injections have a slightly longer half-life

In research contexts, intranasal delivery is often discussed because the nasal cavity provides a unique interface between local mucosal tissue, systemic circulation, and potential nose-to-brain transport pathways

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