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This genetic stratification has profound clinical implications

Given that patients with PCOS often present with gut-derived endotoxemia, LPS-mediated granulosa cell ferroptosis may play a significant role in the pathogenesis of follicular developmental abnormalities in PCOS

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The basic molecular mechanisms involved in these damaging effects include oxidative stress and inflammation-associated intracellular signal transduction pathways

For related formulation context, you can also explore What is the Best Form of Glutathione

CoQ10 supplementation in patients undergoing IVF-ET: the relationship with follicular fluid content and oocyte maturity