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As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period

They do not impair judgment, coordination, or reaction time

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Chromatographic methods can also be used to evaluate purity and monitor changes that may occur while a peptide is being stored

Changes in temperature create extra problems

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