homocysteine and glutathione metabolism (GSH) synthesis. The Methoxistasis: Integrating the Roles of

MAO is localized to the outer mitochondrial membrane, where it catalyzes the oxidative deamination of aromatic amines such as catecholamines and generates H 2 O 2 [41]

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The required reducing equivalents are supplied mainly by the pentose phosphate pathway (PPP) and isocitrate dehydrogenase (IDH) 23,24

It has also been indicated that NIN prevented NAFLD via downregulating the NLRP3/NF-B signalling pathway both in Kupffer cells and in hepatocytes, thus diminishing inflammation in the mice livers (Wang X