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In collaboration with other receptors, integrins activate signal transduction cascades that regulate many cellular activities, including changes in gene expression and cytoskeletal assembly

Thirty-four patients, diagnosed with AIS and receiving reperfusion therapy, were given a dose-escalation of C+P (10/20/50/100 mg) or placebo intravenously at the beginning of endovascular thrombectomy

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The stimulation of the GIP receptor may also promote better post-meal glucose control and improve fat metabolism, which can be especially beneficial for patients struggling with obesity alongside type 2 diabetes

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Any human application would require clinical trial protocols with appropriate institutional oversight and regulatory approval