Hypoxia results in the secretion of hypoxia inducible factor (HIF)-1 by local adipocytes, which stimulates hypoxia response elements on a number of genes including the vascular endothelial growth factor (VEGF) gene and inducing proliferation of stem cells in the adipose tissue (50)
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On the other hand, the combined treatment of selenium and vitamin E as well as selenium alone did not cause significant changes [97]
Neurovascular Interactions in the Nervous System