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The intrinsic solubility determines the amount of neutral compound that can be dissolved in solution

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A previous study indicated that NRF2 is an important and novel transcriptional regulator of ferroptosis in hepatocellular carcinoma (HCC) cells, and NRF2 activation can inhibit ferroptosis in HCC cells [67,68,69]

[2] It is the main and most common cause of vitamin B 12 deficiency anemia in developed countries, [3] and is characterized by a triad of symptoms: [2] Anemia with bone marrow promegaloblastosis (megaloblastic anemia)

Gomisin A also protected SH-SY5Y cells and rat cortical neurons from damage caused by activated microglia through TLR4-mediated NF-B and MAPK signaling inhibition [68]