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Vitamin B12 is cobalamin an enzyme co-factor that is necessary for the synthesis of DNA

But that doesnt necessarily need to be the case, says Wood

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changes in perception including an impaired sense of smell, sensation of pain and paresthesia (skin tingling and numbness, among others

In addition, they induce transcription through protein-protein interactions in the cytosol and by composite binding to other transcription factors at DNA sequences containing GREs and a response element of a distinct transcription factor (85, 87)

I emailed with the natural doctor at the B12 office to find out if she knew of any post menopausal women with similar reactions and was told no