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Release of immune effectors and/or inflammatory polarization of microglia is a logical suspicion, but there may be a more intriguing mechanism at play as suggested by an interesting series of papers by Lisak et al

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Medications Medications used for certain treatment can affect the production of estrogen in our body

Additionally, researchers have identified the presence of rhamnogalacturonan, a bioactive compound in okra seeds, associated with antidiabetic or hypoglycaemic properties [9]

This bioactive compound is derived from the pineal gland, the small endocrine gland in the brain responsible for producing melatonin and regulating circadian rhythms